Sheffield Kidney Institute

Sir,

Thankfully,the retrospective analyses by Dr Heung et al. [1] alert the nephrological community that fluid accumulation is not an innocuous process without clinical consequences but rather a toxic phenomenon that influences patient outcomes adversely. In this study, fluid overload at initiation of renal replacement therapy contributed independently to 1-year mortality and long-term non-recovery (dialysis dependence) of renal function of adult …