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This article has no abstract; the first 100 words appear below.
Focal segmental glomerulosclerosis accounts for approximately 20% of cases of the nephrotic syndrome in children and 40% of such cases in adults, with an estimated incidence of 7 per 1 million.1 It is the most common primary glomerular disorder causing end-stage renal disease in the United States, with a prevalence of 4%.2 The cardinal feature is progressive glomerular scarring. Early in the disease course, glomerulosclerosis is both focal, involving a minority of glomeruli, and segmental, affecting a portion of the glomerular globe. With progression, more widespread and global glomerulosclerosis develops. Since the first clinical–pathological studies of the disease in the . . .
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No potential conflict of interest relevant to this article was reported.
Source Information
From the Department of Pathology, Columbia University College of Physicians and Surgeons (V.D.D.); and the Division of Pediatric Nephrology, Albert Einstein College of Medicine (F.J.K.) — both in New York; and UNC Kidney Center and the Division of Nephrology and Hypertension, University of North Carolina, Chapel Hill (R.J.F.).
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